MITE0000433
MITE0000434
MITE0000435
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description AmyB introduces atropospecific one carbon-carbon and two carbon-nitrogen bonds
Tailoring
  • Biaryl bond formation
  • Other
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: AmyB introduces one C-C and two C-N bonds on the precursor peptide followed by maturation by protease yielding hexapeptide amyxirubin A (AWYIWW) and pentapeptide amyxirubin B (WYIWW)
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000434
Entry StatusStatus: active
Enzyme NameAmyB
Enzyme DescriptionCytochrome P40
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentA cytochrome P450 monooxygenase, AmyB is responsible for the atropospecific formation of one carbon-carbon and two carbon-nitrogen bonds on precursor peptide
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-06-22)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 1 added cofactors."