Reaction 1

• Reaction SMARTS
• Reaction Information

Copy reaction SMARTS

Description	ThdH catalyzes regioselective chlorination of L-tryptophan at the C6 position of its indole ring during the biosynthesis of thienodolin
Tailoring	Halogenation
Database References	No database crosslinks available
Evidence	Heterologous expression Knock-out studies
References	doi:10.1002/cbic.201400016

Example 1

Metadata	Description: Tryptophan 6-halogenase ThdH, could catalyze the regioselective chlorination, as well as bromination, of tryptophan to form 6-chlorotryptophan and 6-bromotryptophan which leds to the production of thienodolin and 6-bromothienodolin, respectively. Intermediate: True
Substrate 1	Copy SMILES
Product 1	Copy SMILES