MITE0000427
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Reaction Information

Number of Known Reactions: 2

Reaction 1
reaction SMARTS
Description Rdc2 catalyzes the regioselective chlorination of a late-stage intermediate (monocillin II to pochonin D) during radicicol biosynthesis
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Reaction 2
reaction SMARTS
Description Rdc2 can also halogenate hydroxyisoquinoline to produce chlorinated hydroxyisoquinolines
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000427
Entry StatusStatus: active
Enzyme NameRdc2
Enzyme DescriptionHalogenase
Database References
Cofactors
  • Organic
    • FAD
References
CommentRdc2 is a flavin-dependent halogenase involved in the biosynthesis of the fungal metabolite radicicol.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-07-01)

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Comment "New entry."