MITE0000426
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description CitB catalyzes the oxidative formation of C–C and C–O cross-links within the CitA precursor peptide and MxPep is responsible for maturation of the peptide by removing the leader sequence generating the intermediate product cittilin B.
Tailoring
  • Biaryl bond formation
  • Oxidation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000426
Entry StatusStatus: active
Enzyme NameCitB
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentCitB is a cytochrome P450 monooxygenase that catalyzes the formation biaryl and aryl-oxygen-aryl ether bonds in the core tetrapeptide (YIYY)
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-07-03)

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Reviewer(s)
Comment "New entry."