MITE0000400
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description The preferred order of events in monensin biosynthesis is hydroxylation at C-26 catalysed by MonD, followed by O-methylation at the hydroxy group at C-3 catalysed by MonE
Tailoring
  • Hydroxylation
Database References No database crosslinks available
Evidence
  • Inference from genomic data and chemical structure
References
Example 1
Metadata
  • Description: MonD catalyzes hydroxylation at C-26 of dehydroxydemethylmonensin to produce intermediate demethylmonensin
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000400
Entry StatusStatus: active
Enzyme NameMonD
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentMonensin hydroxylase
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-27)

Contributor(s)
Reviewer(s)
Comment "New entry."