Reaction 1

• Reaction SMARTS
• Reaction Information

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Description	MonE catalyzes O-methylation of the hydroxy group at C-3 of demethylmonensin
Tailoring	Methylation
Database References	No database crosslinks available
Evidence	Inference from genomic data and chemical structure Knock-out studies
References	doi:10.1046/j.1365-2958.2003.03571.x doi:10.3762/bjoc.10.34 doi:10.1038/s41467-023-41889-0

Example 1

Metadata	Description: After hydroxylation by MonD and O-methylation by MonE, the ACP-bound product is hydrolysed by MonCII (thioesterase) to release free monensin A Intermediate: True
Substrate 1	Copy SMILES
Product 1	Copy SMILES