MITE0000451
MITE0000452
MITE0000453
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Oxidation of the arylamine group of aminopyrrolnitrin to the corresponding arylnitro group in pyrrolnitrin.
Tailoring
  • Monooxygenation
  • Oxidation
Database References
Evidence
  • Heterologous expression
  • In vitro assay
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: Oxidation of the arylamine group of aminopyrrolnitrin to the corresponding arylnitro group in pyrrolnitrin
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000452
Entry StatusStatus: active
Enzyme NamePrnD
Enzyme DescriptionRieske N-oxygenase
Database References
Cofactors
  • Organic
    • Flavin mononucleotide
    • NADP
  • Inorganic
    • Fe
    • FeS
References
CommentPrnD (aminopyrrolnitrin oxygenase) catalyzes the final N-oxygenation step in pyrrolnitrin biosynthesis, converting aminopyrrolnitrin into pyrrolnitrin by oxidation of an arylamine to an arylnitro group
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-14)

Contributor(s)
Reviewer(s)
Comment "New entry."