Minimum Information about a Tailoring Enzyme Repository

MITE0000452

MITE0000453

MITE0000454

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Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	The cytochrome P450 monooxygenase btcC further catalyzes the multistep oxidation of betaestacin IV to produce several compounds, including betaestacins Va, Vb, Vc and VI
Tailoring	Oxidation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1016/j.tetlet.2018.02.022

Example 1

Metadata	Description: The cytochrome P450 monooxygenase btcC further catalyzes the multistep oxidation of betaestacin IV to produce several compounds, including betaestacins Va, Vb, Vc and VI Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000453
Entry Status	Status: active
Enzyme Name	btcC
Enzyme Description	Cytochrome P450 monooxygenase
Database References	UniProtKB: A0A2Z6FZ20 NCBI GenPept: BBE36500.1 MIBiG: BGC0001528
Cofactors	Organic Heme Inorganic Fe
References	doi:10.1016/j.tetlet.2018.02.022
Comment	The cytochrome P450 monooxygenase btcC further catalyzes the multistep oxidation of betaestacin IV to produce several compounds, including betaestacins Va, Vb, Vc and VI
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-06)

Contributor(s)	0009-0008-4645-6771
Reviewer(s)	0000-0002-9747-3423 0000-0001-6534-6609
Comment	"New entry. Reviewer 2 fixed the entry cross-references with MIBiG."