MITE0000440
MITE0000441
MITE0000442
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description SlnM, performs an unprecedented function by formation of the Δ18,19 double bond and bis(spiroacetal)
Tailoring
  • Dehydration
  • Other
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: SlnM, a methyltransferase homologue, utilizes SAM as a co‐factor, for the formation of Δ18,19 double bond and bis(spiroacetal) in the last step of salinomycin biosynthesis.
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000441
Entry StatusStatus: active
Enzyme NameSlnM
Enzyme DescriptionO-methyltransferase
Database References
Cofactors
  • Organic
    • SAM
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-06-01)

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Comment "New entry."