Reaction 1

• Reaction SMARTS
• Reaction Information

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Description	The P450 monooxygenase SlnF performs the hydroxylation at C-20 in cognate with ferredoxin SlnE
Tailoring	Hydroxylation Oxidation
Database References	No database crosslinks available
Evidence	Inference from genomic data and chemical structure Knock-out studies
References	doi:10.1128/AEM.06701-11 doi:10.3390/md20060393

Example 1

Metadata	Description: The final steps of salinomycin assembly involve C-20 hydroxylation by SlnE/SlnF followed by polyether chain release from the PKS by thioesterases SlnDI/SlnDII. Lastly, the methyltransferase-like enzyme SlnM catalyzes the spirocyclization-coupled dehydration of OH-19 and forms the final product salinomycin. Intermediate: True
Substrate 1	Copy SMILES
Product 1	Copy SMILES