MITE0000441
MITE0000442
MITE0000443
Modify entry

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description The hydro-2,2′-bifuran region of pre-lysocellin is oxidized by LyoI to form a hydro-2,2′-bifuran-2-ol (hemiketal) moiety, resulting in the final lysocellin product.
Tailoring
  • Hydroxylation
  • Oxidation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000442
Entry StatusStatus: active
Enzyme NameLyoI
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentLyoI performs hydro-2,2′-bifuran oxidation in the polyether ionophore Lysocellin
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-06-01)

Contributor(s)
Reviewer(s)
Comment "New entry."