Minimum Information about a Tailoring Enzyme Repository

MITE0000403

MITE0000404

MITE0000405

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Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Chlorination of CMA-S-CmaD
Tailoring	Halogenation
Database References	No database crosslinks available
Evidence	Heterologous expression In vitro assay
References	doi:10.1038/nature03797

Example 1

Metadata	Description: Single chlorination of CMA thioester Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000404
Entry Status	Status: active
Enzyme Name	CmaB
Enzyme Description	Non-heme halogenase
Database References	UniProtKB: Q87W55 NCBI GenPept: AAO58149.1
Cofactors	Organic a-Ketoglutaric acid Inorganic Fe
References	doi:10.1038/nature03797
Comment	γ-halogenation of a carrierbound-S-alloisoleucine (CMA-S-CmaD) as intermediate product for cyclopropyl amino acid biosynthesis through CmaC
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-06-18)

Contributor(s)	0009-0000-8651-1669
Reviewer(s)	0000-0001-6534-6609
Comment	"New entry. Replaced chiral structures with flat ones due to validation engine incompatibility."