MITE0000340
MITE0000341
MITE0000342
Modify entry

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Carboxyamidation of terminal galacturonate of nosokomycin A with ammonia as a donor substrate
Tailoring
  • Other
Database References No database crosslinks available
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: carboxyamidation of ammonia ion and nosokomycin A
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000341
Entry StatusStatus: active
Enzyme NameMoeH5
Enzyme DescriptionGAT superfamily amidotransferase
Database References
Cofactors
  • Organic
    • Adenosine triphosphate
  • Inorganic
    • Mg
References
CommentMoeH5 is a flexible carbohydrate tailoring enzyme performing carboxyamidation using substrates, such as glycine, ammonia and C5N unit to convert the carboxyl group of terminal sugar of moenomycins (galacturonic acid) into carboxyamidated products - nosokomycins B, moenomycin G, moenomycin A
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-04-20)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 2 made reaction more generalized by removing balancing reactants O, N."