MITE0000462
MITE0000463
MITE0000464
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Chlorination of tryptophan at C7 position to yield 7-chloro-L-tryptophan in pyrrolnitrin biosynthesis
Tailoring
  • Halogenation
Database References
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: Chlorination of tryptophan at C7 position to yield 7-chloro-L-tryptophan in pyrrolnitrin biosynthesis
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000463
Entry StatusStatus: active
Enzyme NamePrnA
Enzyme DescriptionTryptophan 7-halogenase
Database References
Cofactors
  • Organic
    • FAD
References
CommentCatalyzes chlorination of tryptophan at C7 position to yield 7-chloro-L-tryptophan in pyrrolnitrin biosynthesis
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-06)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 1 added EC number. Reviewer 2 fixed crossref to MIBiG."