Reaction 1

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Description	Phosphate-dependent purine nucleoside phosphorylase that catalyzes the reversible phosphorolysis of 5′-fluoro-5′-deoxyadenosine (5′-FDA), yielding adenine and a fluorinated sugar phosphate. This reaction constitutes a key step in microbial organofluorine biosynthesis, channeling fluorinated intermediates toward fluoroacetate and 4-fluorothreonine production. Gene inactivation abolishes downstream fluorometabolite formation, supporting its essential role in pathway flux.
Tailoring	Other
Database References	RHEA: 19805 BRENDA: 2.4.2.1 Expasy ENZYME: 2.4.2.1
Evidence	Inference from genomic data and chemical structure In vitro assay Knock-out studies
References	doi:10.1016/j.pep.2019.105508 doi:10.1016/j.bioorg.2012.06.002 doi:10.1016/j.bioorg.2007.04.001

Example 1

Metadata	Description: Phosphate-dependent phosphorolysis of 5′-fluoro-5′-deoxyadenosine, cleaving the N-glycosidic bond to yield adenine and a fluorinated ribose-1-phosphate (5-fluoro-5-deoxyribose-1-phosphate) Intermediate: False
Substrate 1	Copy SMILES
Product 1	Copy SMILES