MITE0000423
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description BarH catalyzes the terminal oxidative decarboxylation and final dehydrogenation that generates a thiazole ring from a thiazoline intermediate during the biosynthesis of barbamide
Tailoring
  • Decarboxylation
  • Dehydrogenation
Database References No database crosslinks available
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000423
Entry StatusStatus: active
Enzyme NameBarH
Enzyme DescriptionNon-Heme Diiron Monooxygenase
Database References
Cofactors
  • Organic
    • Ascorbic acid
  • Inorganic
    • Fe
References
CommentBarH performs the terminal oxidative decarboxylation to form fully oxidized, conjugated thiazole ring in the biosynthesis of barbamide
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-07-05)

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Reviewer(s)
Comment "New entry."