Minimum Information about a Tailoring Enzyme Repository

MITE0000409

MITE0000410

MITE0000411

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Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	O-glycosylation of polyene aglycon
Tailoring	Glycosylation
Database References	No database crosslinks available
Evidence	Inference from genomic data and chemical structure In vitro assay
References	doi:10.1007/s00253-004-1802-4 doi:10.1002/cbic.200800349

Example 1

Metadata	Description: O-glycosylation of nystatin A1 aglycon with mycosamine group to yield final product nystatin A1. Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000410
Entry Status	Status: active
Enzyme Name	NysDI
Enzyme Description	Mycosaminyltransferase
Database References	UniProtKB: Q9L4W6 NCBI GenPept: AAF71773.1 MIBiG: BGC0000115
Cofactors	Inorganic Mg
References	doi:10.1007/s00253-004-1802-4 doi:10.1002/cbic.200800349
Comment	Glycosyltransferase involved in the last biosynthetic step of nystatin A1.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-04-14)

Contributor(s)	0000-0001-5730-3326
Reviewer(s)	0000-0003-4819-2251
Comment	"New entry. Reviewer 1 fixed reaction SMARTS and substrate/product SMILES, reaction description, evidence qualifier, refereces."