MITE0000382
MITE0000383
MITE0000384
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description GroI incorporates a keto group at C-17 of gromomycin C, leading to the formation of gromomycin B
Tailoring
  • Monooxygenation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • Knock-out studies
References
Example 1
Metadata
  • Description: GroI incorporates a keto group at C-17 of gromomycin C, leading to the formation of gromomycin B
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000383
Entry StatusStatus: active
Enzyme NameGroI
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentGroI oxidizes the allylic C-17 position of gromomycin C to form a keto group
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-24)

Contributor(s)
Reviewer(s)
Comment "New entry."