MITE0000380
MITE0000381
MITE0000382
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Cyclization of meroterpenoid intermediate in the ascofuranone biosynthetic pathway.
Tailoring
  • Cyclization
Database References
Evidence
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Converts 16-hydroxy-ilicicolin A epoxide to ascofuranol by cyclisation to form a tetrahydrofuran ring.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000381
Entry StatusStatus: active
Enzyme NameAscI
Enzyme DescriptionTerpene cyclase
Database References
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-16)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 1 fixed reaction SMARTS and product, added RHEA ID and EC number, improved reaction descriptions."