MITE0000376
MITE0000377
MITE0000378
Modify entry

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Epoxidation in intermediate meroterpenoid in the ascochlorin/ascofuranone biosynthetic pathway.
Tailoring
  • Oxidation
Database References
Evidence
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Converts Ilicicolin A to Ilicicolin A epoxide by stereoselective epoxidation of the terminal double bond of the prenyl group.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000377
Entry StatusStatus: active
Enzyme NameAscE
Enzyme DescriptionCytochrome P450/NADPH P450 reductase
Database References
Cofactors
  • Organic
    • Heme
    • NADP
  • Inorganic
    • Fe
References
CommentBifunctional cytochrome P450/NADPH P450 reductase
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-16)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 1 improved reaction description, added RHEA crossref, specified Fe, Heme as cofactors."