Minimum Information about a Tailoring Enzyme Repository

MITE0000359

MITE0000360

MITE0000361

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Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Reduction of meroterpenoid intermediate andilesin B in the andilesin biosynthetic pathway.
Tailoring	Reduction
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1021/ja508127q

Example 1

Metadata	Description: Conversion of andilesin B to andilesin C. Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000360
Entry Status	Status: active
Enzyme Name	AndH
Enzyme Description	Short-chain dehydrogenase/reductase
Database References	UniProtKB: A0A097ZPD4 NCBI GenPept: BAP81862.1 MIBiG: BGC0002612
References	doi:10.1021/ja508127q
Comment	Andilesin B originates from the spontaneous elimination of acetate from Acetylandilesin A (produced by AndG). AndH reduces Andilesin B to produce Andilesin C.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-17)

Contributor(s)	0000-0002-0771-9611
Reviewer(s)	0000-0001-6534-6609
Comment	"New entry. Reviewer 1 improved reaction descriptions."