Minimum Information about a Tailoring Enzyme Repository

MITE0000347

MITE0000348

MITE0000349

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Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Site-specific chlorination of pyrrolic heterocycles.
Tailoring	Halogenation
Database References	No database crosslinks available
Evidence	In vitro assay
References	doi:10.1038/s42004-023-01083-1

Example 1

Metadata	Description: Chlorination of monodechloroaminopyrrolnitrin to form aminopyrrolnitrin. Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000348
Entry Status	Status: active
Enzyme Name	PrnC
Enzyme Description	Flavin-dependent halogenase
Database References	UniProtKB: P95482 NCBI GenPept: AAB97506.1
Cofactors	Organic FAD
References	doi:10.1038/s42004-023-01083-1 doi:10.1002/1615-4169(200108)343:6/7%3C591::AID-ADSC591%3E3.0.CO;2-E
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-03)

Contributor(s)	0000-0001-9487-1525
Reviewer(s)	0000-0002-9747-3423 0000-0001-6534-6609
Comment	"New entry. Reviewer 2 removed MIBiG BGC cross-reference (was BGC0000924) since it describes the gene cluster from Pseudomonas chlororaphis, while the paper describes the one from Pseudomonas fluorescens."