MITE0000313
MITE0000314
MITE0000315
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Reaction Information

Number of Known Reactions: 2

Reaction 1
reaction SMARTS
Description Oxidative cyclization (ether bond formation) of a depside to a depsidone.
Tailoring
  • Cyclization
Database References
Evidence
  • Heterologous expression
  • Inference from genomic data and chemical structure
  • In vitro assay
References
Example 1
Metadata
  • Description: Catalyze hypoprotocetratic acid from 4-O-demethylbarabatic acid.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Reaction 2
reaction SMARTS
Description C-8 hydroxylation of a depside to a depsidone.
Tailoring
  • Hydroxylation
Database References
Evidence
  • Heterologous expression
  • Inference from genomic data and chemical structure
  • In vitro assay
References
Example 1
Metadata
  • Description: Conversion of hypoprotocetratic acid to convirensic acid.
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000314
Entry StatusStatus: active
Enzyme NameDsd3
Enzyme DescriptionCytochrome P450 monooxygenase
Database References
Cofactors
  • Organic
    • Heme
    • NADP
  • Inorganic
    • Fe
References
CommentCatalyzes ether bond formation and C-8 hydroxylation of 4-O-demethylbarbatic acid to produce convirensic acid.
Enzyme Visualization (AlphaFold-predicted) UniProt ID not available - could not render visualization

Version 1 (2026-04-13)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."

Version 2 (2026-04-25)

Contributor(s)
Reviewer(s)
Comment "Added additional reaction."