MITE0000420
MITE0000421
MITE0000422
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description BytO catalyzes C–N biaryl cross-link between histidine and tyrosine of precursor peptide (MNYLH)
Tailoring
  • Biaryl bond formation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
References
Example 1
Metadata
  • Description: BytO catalyzes C–N biaryl cross-link within the BytA precursor peptide (MNYLH), generating the characteristic bicyclic scaffold of myxarylin
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000421
Entry StatusStatus: active
Enzyme NameBytO
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentBytO installs C–N biaryl linkage in the myxarylin biosynthesis and also demonstrated broad substrate tolerance
Enzyme Visualization (AlphaFold-predicted) UniProt ID not available - could not render visualization

Version 1 (2026-07-07)

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Reviewer(s)
Comment "New entry."