MITE0000385
MITE0000386
MITE0000387
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description O-methylation of fusicoccin terpene scaffold to yield methylated derivatives.
Tailoring
  • Methylation
Database References No database crosslinks available
Evidence
  • Inference from genomic data and chemical structure
  • In vitro assay
References
Example 1
Metadata
  • Description: Methylation of fusicoccin Q to yield fusicoccin P, intermediate in the biosynthetic patwhay of fusicoccin A. Could not be demonstrated in vitro due to unavaialability of substrate, inferred.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Example 2
Metadata
  • Description: Methylation of fusicoccin H aglycon to 16-O-methyl derivative, observed in vitro in trace amounts.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Example 3
Metadata
  • Description: Methylation of fusicoccin H to yield 16-O-methyl-fusicoccin H, observed in vitro but not main step of the biosynthetic pathway.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000386
Entry StatusStatus: active
Enzyme NamePaMT
Enzyme DescriptionO-Methyltransferase
Database References
Cofactors
  • Organic
    • SAM
References
CommentMethylation of Fusicoccin Q to give Fusicoccin P and related terpenoid intermediates.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-05-15)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 1 revised SMARTS/SMILES, added side reactions observed in vitro, added cofactor information."