{
    "accession": "MITE0000454",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2026-05-06",
            "contributors": [
                "0000-0001-9487-1525"
            ],
            "reviewers": [
                "0009-0008-3623-3734"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "RedG",
        "description": "Rieske-oxygenase-like enzyme",
        "references": [
            "doi:10.1038/nchem.1024"
        ],
        "databaseIds": {
            "uniprot": "O54095",
            "genpept": "CAA16434.1",
            "mibig": "BGC0001063"
        },
        "cofactors": {
            "organic": [
                "NADP"
            ],
            "inorganic": [
                "FeS"
            ]
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Cyclization"
            ],
            "description": "Cyclization of undecylprodigiosin into streptorubin B",
            "reactionSMARTS": "[#6:1]-[#6:2]-[#6:3]-[#6:4]-[#6:5]-[#6:6]-[#6:7]-[#6:8]-[#6:9]-[#6:10]-[#6:11]-[#6:12]1:[#7:16]:[#6:15](-[#6:17]=[#6:18]2-[#6:19](-[#8:28]-[#6:29])=[#6:20]-[#6:21](-[#6:23]3:[#7:27]:[#6:26]:[#6:25]:[#6:24]:3)=[#7:22]-2):[#6:14]:[#6:13]:1>>[#6:1]-[#6:2]-[#6:3]-[#6:4]/[#6@@:5]1-[#6:14]2:[#6:15](-[#6:17]=[#6:18]3-[#6:19](-[#8:28]-[#6:29])=[#6:20]-[#6:21](-[#6:23]4:[#7:27]:[#6:26]:[#6:25]:[#6:24]:4)=[#7:22]-3):[#7:16]:[#6:12](:[#6:13]:2)-[#6:11]-[#6:10]-[#6:9]-[#6:8]-[#6:7]-[#6:6]-1",
            "reactions": [
                {
                    "substrate": "CCCCCCCCCCCc1ccc(/C=C2\\N=C(c3ccc[nH]3)C=C2OC)[nH]1",
                    "products": [
                        "CCCC[C@H]1CCCCCCc2cc1c(C=C1N=C(c3ccc[nH]3)C=C1OC)[nH]2"
                    ],
                    "isIntermediate": true,
                    "description": "Cyclization of undecylprodigiosin into streptorubin B"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Inference from genomic data and chemical structure",
                    "Knock-out studies"
                ],
                "references": [
                    "doi:10.1038/nchem.1024"
                ]
            }
        }
    ]
}