{
    "accession": "MITE0000445",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2026-05-29",
            "contributors": [
                "0000-0001-9260-4650"
            ],
            "reviewers": [
                "0000-0002-4540-6501"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "NanB",
        "description": "Acetyltransferase",
        "references": [
            "doi:10.1021/jacs.0c01605"
        ],
        "databaseIds": {
            "uniprot": "A0A6G9KH50",
            "genpept": "QIQ51362.1"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Acetylation"
            ],
            "description": "Acetylation of an intermediate to produce nanangelenin F.",
            "reactionSMARTS": "[#6:1]12-[#7:9]-[#6:11](=[#8:12])-[#6@@:10](-[#7:14]-[#6:15](=[#8:17])-[#6:16]3:[#6:21]:[#6:22]:[#6:20]:[#6:18]:[#6:19]:3-[#7:23](-[#8:25])-[#6:24](-[#6:28])(-[#6:27])-[#6:26]=[#6:29])-[#6:8]-[#6:7](=[#8:13])-[#6:5]:1:[#6:6]:[#6:4]:[#6:2]:[#6:3]:2>>[#6:1]12:[#6:3]:[#6:2]:[#6:4]:[#6:6]:[#6:5]:1-[#6:7](=[#8:13])-[#6:8]-[#6@:10](-[#7:14]-[#6:15](-[#6:16]1:[#6:19](-[#7:23](-[#6:24](-[#6:26]=[#6:29])(-[#6:28])-[#6:27])-[#8:25]-[#6](=[#8])-[#6]):[#6:18]:[#6:20]:[#6:22]:[#6:21]:1)=[#8:17])-[#6:11](=[#8:12])-[#7:9]-2",
            "reactions": [
                {
                    "substrate": "C=CC(C)(C)N(O)c1ccccc1C(=O)N[C@H]1CC(=O)c2ccccc2NC1=O",
                    "products": [
                        "C=CC(C)(C)N(OC(C)=O)c1ccccc1C(=O)N[C@H]1CC(=O)c2ccccc2NC1=O"
                    ],
                    "isIntermediate": true,
                    "description": "Acetylation"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Heterologous expression"
                ],
                "references": [
                    "doi:10.1021/jacs.0c01605"
                ]
            }
        }
    ]
}