{
    "accession": "MITE0000364",
    "status": "active",
    "comment": "Converts Colletorin D into Colletochlorin D and Colletorin B into Colletochlorin B.",
    "changelog": [
        {
            "version": "1",
            "date": "2026-05-06",
            "contributors": [
                "0000-0002-0771-9611"
            ],
            "reviewers": [
                "0000-0001-9078-9292"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "CTC2",
        "description": "Halogenase",
        "references": [
            "doi:10.1016/j.ymben.2023.10.002"
        ],
        "databaseIds": {
            "uniprot": "A0A1B7YCJ8",
            "genpept": "OBR09776.1",
            "mibig": "BGC0002812"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Halogenation"
            ],
            "description": "Chlorination of Colletorin D to produce Colletochlorin D",
            "reactionSMARTS": "CC(C)=CCc1c(O)cc(C)c(C=O)c1O>>CC(C)=CCc1c(O)c(Cl)c(C)c(C=O)c1O",
            "reactions": [
                {
                    "substrate": "CC(C)=CCc1c(O)cc(C)c(C=O)c1O",
                    "products": [
                        "CC(C)=CCc1c(O)c(Cl)c(C)c(C=O)c1O"
                    ],
                    "isIntermediate": false
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Heterologous expression"
                ],
                "references": [
                    "doi:10.1016/j.ymben.2023.10.002"
                ]
            }
        }
    ]
}
