{
    "accession": "MITE0000325",
    "status": "retired",
    "retirementReasons": [
        "KinO is involved in precursor biosynthesis and not a tailoring enzyme per se."
    ],
    "comment": "Monooxygenation in the ornithine N5 position",
    "changelog": [
        {
            "version": "1",
            "date": "2026-04-15",
            "contributors": [
                "0000-0003-2163-5526"
            ],
            "reviewers": [
                "0000-0002-9747-3423",
                "0000-0001-5863-7248"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "KinO",
        "description": "Lysine/ornithine N-oxygenase",
        "references": [
            "doi:10.64898/2026.02.23.707395"
        ],
        "databaseIds": {
            "genpept": "MHN9096792.1"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Monooxygenation"
            ],
            "description": "Monooxygenation in the ornithine N5 position",
            "reactionSMARTS": "[#6:1](-[#6:8]-[#7:9])-[#6:2]-[#6@:3](\\[#7:7])-[#6:4](-[#8:6])=[#8:5]>>[#6:1](-[#6:8]-[#7:9]-[#8])-[#6:2]-[#6@:3](\\[#7:7])-[#6:4](-[#8:6])=[#8:5]",
            "reactions": [
                {
                    "substrate": "NCCC[C@H](N)C(=O)O",
                    "products": [
                        "N[C@@H](CCCNO)C(=O)O"
                    ],
                    "isIntermediate": false,
                    "description": "Monooxygenation in the ornithine N5 position"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Inference from genomic data and chemical structure"
                ],
                "references": [
                    "doi:10.64898/2026.02.23.707395"
                ]
            }
        }
    ]
}