{
    "accession": "MITE0000324",
    "status": "retired",
    "retirementReasons": [
        "ObiH is involved in precursor biosynthesis and not a tailoring enzyme per se."
    ],
    "comment": "Aldehydes are converted to the corresponding \u03b2-hydroxy-\u03b1-amino acids by Transaldolase ObiH",
    "changelog": [
        {
            "version": "1",
            "date": "2026-04-13",
            "contributors": [
                "0000-0002-6077-7490"
            ],
            "reviewers": [
                "0000-0002-9747-3423",
                "0000-0001-5863-7248"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "ObiH",
        "description": "Transaldolase",
        "references": [
            "doi:10.1038/s41467-019-11383-7"
        ],
        "databaseIds": {
            "uniprot": "A0A1X9LWZ7",
            "genpept": "ARJ35753.1"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Other"
            ],
            "description": "Transaldolase",
            "reactionSMARTS": "[#6:1]1(-[#6:7]-[#6:8](=[#8])):[#6:2]:[#6:3]:[#6:4]:[#6:5]:[#6:6]:1>>[#6:1]1(-[#6:7]-[#6:8](-[#8])-[#6](-[#7])-[#6](=[#8])-[#8]):[#6:6]:[#6:5]:[#6:4]:[#6:3]:[#6:2]:1",
            "reactions": [
                {
                    "substrate": "O=CCc1ccccc1",
                    "products": [
                        "NC(C(=O)O)C(O)Cc1ccccc1"
                    ],
                    "isIntermediate": true,
                    "description": "Aldehydes are converted to the corresponding \u03b2-hydroxy-\u03b1-amino acids by Transaldolase ObiH"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "In vitro assay"
                ],
                "references": [
                    "doi:10.1038/s41467-019-11383-7"
                ]
            }
        }
    ]
}