{
    "accession": "MITE0000313",
    "status": "active",
    "comment": "Oxidizes the C-8 alcohol of convirensic acid into the aldehyde group of virensic acid.",
    "changelog": [
        {
            "version": "1",
            "date": "2026-04-13",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0002-9747-3423"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "Dsd6",
        "description": "FAD-linked oxidoreductase (Alcohol Oxidase)",
        "references": [
            "doi:10.1111/nph.70731"
        ],
        "databaseIds": {
            "genpept": "XRW97415.1"
        },
        "cofactors": {
            "organic": [
                "FAD"
            ]
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Oxidation"
            ],
            "description": "Oxidation of the C-8 hydroxymethyl group to a formyl (aldehyde) group.",
            "reactionSMARTS": "[#8:1]=[#6:2]1-[#6:20]2:[#6:21](:[#6:23]:[#6:24](-[#8:25]):[#6:8](-[#6:9]-[#8]):[#6:7]:2-[#8:6]-[#6:5]2:[#6:10](:[#6:12](-[#6:17](=[#8:19])-[#8:18]):[#6:13](:[#6:15](-[#6:16]):[#6:4]:2-[#8:3]-1)-[#8:14])-[#6:11])-[#6:22]>>[#8:1]=[#6:2]1-[#6:20]2:[#6:21](:[#6:23]:[#6:24](-[#8:25]):[#6:8](-[#6:9]=[#8:1]):[#6:7]:2-[#8:6]-[#6:5]2:[#6:10](:[#6:12](-[#6:17](=[#8:19])-[#8:18]):[#6:13](:[#6:15](-[#6:16]):[#6:4]:2-[#8:3]-1)-[#8:14])-[#6:11])-[#6:22]",
            "reactions": [
                {
                    "substrate": "Cc1cc(O)c(CO)c2c1C(=O)Oc1c(C)c(O)c(C(=O)O)c(C)c1O2",
                    "products": [
                        "Cc1cc(O)c(C=O)c2c1C(=O)Oc1c(C)c(O)c(C(=O)O)c(C)c1O2"
                    ],
                    "isIntermediate": false,
                    "description": "Oxidation of Convirensic acid to Virensic acid."
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Heterologous expression",
                    "Inference from genomic data and chemical structure",
                    "In vitro assay"
                ],
                "references": [
                    "doi:10.1111/nph.70731"
                ]
            },
            "databaseIds": {
                "ec": "1.1.1.1"
            }
        }
    ]
}