{
    "accession": "MITE0000304",
    "status": "active",
    "comment": "Cytochrome P450 mediated C-H oxidation, hydroxylation",
    "changelog": [
        {
            "version": "1",
            "date": "2026-04-15",
            "contributors": [
                "0000-0003-2971-646X"
            ],
            "reviewers": [
                "0000-0002-9747-3423"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "TraB",
        "description": "Cytochrome P450",
        "references": [
            "doi:10.1007/s00253-021-11674-4"
        ],
        "databaseIds": {
            "uniprot": "A0A481WNM6",
            "genpept": "QBK15050.1"
        },
        "cofactors": {
            "inorganic": [
                "Fe"
            ]
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Hydroxylation",
                "Oxidation"
            ],
            "description": "Cytochrome P450 mediated C-H oxidation",
            "reactionSMARTS": "[#6:1]1(-[#8:8])=[#6:2](-[#6:9](=[#8:11])-[#6:10]-[#6:12]-[#6:13]-[#6:14]-[#6:15])-[#6:3](=[#8:6])-[#8:4]-[#6@:5]-1/[#6:7]-[#6:16](=[#8:18])-[#8:17]>>[#6:1]1(-[#8:8])=[#6:2](-[#6:9](=[#8:11])-[#6:10]-[#6:12]-[#6@@:13](\\[#8])-[#6:14]-[#6:15])-[#6:3](=[#8:6])-[#8:4]-[#6@:5]-1/[#6:7]-[#6:16](=[#8:18])-[#8:17]",
            "reactions": [
                {
                    "substrate": "CCCCCC(=O)C1=C(O)[C@H](CC(=O)O)OC1=O",
                    "products": [
                        "CC[C@H](O)CCC(=O)C1=C(O)[C@H](CC(=O)O)OC1=O"
                    ],
                    "isIntermediate": true,
                    "description": "Cytochrome P450 mediated C-H oxidation"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Heterologous expression",
                    "Inference from genomic data and chemical structure",
                    "Knock-out studies"
                ],
                "references": [
                    "doi:10.1007/s00253-021-11674-4"
                ]
            }
        }
    ]
}