{
    "accession": "MITE0000300",
    "status": "active",
    "comment": "PbsCD is responsible for the ortho-hydroxylation of phenylalanine residue in PbsA1-4 precursor peptides analogue to biphenomycin ",
    "changelog": [
        {
            "version": "1",
            "date": "2026-03-26",
            "contributors": [
                "0000-0002-3947-4444"
            ],
            "reviewers": [
                "0000-0002-9747-3423",
                "0000-0001-6534-6609"
            ],
            "comment": "New entry. Added new MNIO enzyme PbsC (+PbsD partner). Reviewer 2 replaced retired UniProtKB IDs with UniParc Ids."
        }
    ],
    "enzyme": {
        "name": "PbsC",
        "description": "Multinuclear nonheme Fe-dependent oxidative enzyme",
        "references": [
            "doi:10.1021/jacs.5c06044"
        ],
        "auxiliaryEnzymes": [
            {
                "name": "PbsD",
                "description": "RRE-containing partner protein",
                "databaseIds": {
                    "uniprot": "UPI000F633073",
                    "genpept": "RRN73830.1"
                }
            }
        ],
        "databaseIds": {
            "uniprot": "UPI000F64476A",
            "genpept": "RRN73831.1"
        },
        "cofactors": {
            "inorganic": [
                "Fe"
            ]
        }
    },
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            "reactions": [
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                    ],
                    "isIntermediate": true,
                    "description": "Hydroxylation of Phe8 and Phe10 residues in PbsA3 precursor peptide"
                }
            ],
            "evidence": {
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                "references": [
                    "doi:10.1021/jacs.5c06044"
                ]
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}
