{
    "accession": "MITE0000275",
    "status": "active",
    "comment": "Transferring the acyl group on the pyranoquinone ",
    "changelog": [
        {
            "version": "1",
            "date": "2026-04-13",
            "contributors": [
                "0000-0001-5730-3326"
            ],
            "reviewers": [
                "0000-0002-9747-3423"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "MppB",
        "description": "acyltransferase",
        "references": [
            "doi:10.1007/s00253-013-4745-9"
        ],
        "databaseIds": {
            "uniprot": "R9UMI5",
            "genpept": "AGN71607.1",
            "mibig": "BGC0000027"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Acylation"
            ],
            "description": "Transferring the acyl group on the pyranoquinone",
            "reactionSMARTS": "[#8:1]=[#6:2]1-[#6:16]=[#6:15]2-[#6:7](=[#6:8]-[#8:9]-[#6:10](=[#6:14]-2)-[#6:11]=[#6:12]-[#6:13])-[#6:6](=[#8:17])-[#6@@:3]-1(/[#8:5])-[#6:4]>>[#8:1]=[#6:2]1-[#6:16]=[#6:15]2-[#6:7](=[#6:8]-[#8:9]-[#6:10](=[#6:14]-2)-[#6:11]=[#6:12]-[#6:13])-[#6:6](=[#8:17])-[#6@@:3]-1(-[#8:5]-[#6](=[#8])-[#6](=[#8])-[#6]-[#6]-[#6]-[#6]-[#6])/[#6:4]",
            "reactions": [
                {
                    "substrate": "C/C=C/C1=CC2=CC(=O)[C@@](C)(O)C(=O)C2=CO1",
                    "products": [
                        "CC=CC1=CC2=CC(=O)[C@@](C)(OC(=O)C(=O)CCCCC)C(=O)C2=CO1"
                    ],
                    "isIntermediate": true,
                    "description": "Transferring the acyl group on the pyranoquinone"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Knock-out studies"
                ],
                "references": [
                    "doi:10.1007/s00253-013-4745-9"
                ]
            }
        }
    ]
}