{
    "accession": "MITE0000270",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2026-03-26",
            "contributors": [
                "0000-0002-6077-7490"
            ],
            "reviewers": [
                "0000-0002-9747-3423"
            ],
            "comment": "New entry."
        }
    ],
    "enzyme": {
        "name": "Luc1",
        "description": "Methyltransferase",
        "references": [
            "doi:10.1038/s41429-022-00529-3",
            "doi:10.1080/09168451.2020.1725419",
            "doi:10.1016/j.chembiol.2013.07.004"
        ],
        "databaseIds": {
            "uniprot": "A0A6J4B4P7",
            "genpept": "BBQ09592.1"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Methylation"
            ],
            "description": "demethyllucilactaene to Lucilactaene by the methyltransferase Luc1",
            "reactionSMARTS": "[#7]1-[#6:24]2(-[#6]-[#6]-[#8]-[#6]-2-[#6:3](-[#6:4](=[#8:8])-[#6:5](-[#6:9])=[#6:6]-[#6:10]=[#6:11]-[#6:12]=[#6:13]-[#6:14]=[#6:15](-[#6:20])-[#6:16]=[#6:17](-[#6](=[#8])-[#8])-[#6:19])-[#6:2]-1=[#8:7])-[#8]>>[#7]1-[#6:24]2(-[#6]-[#6]-[#8]-[#6]-2-[#6:3](-[#6:4](=[#8:8])-[#6:5](-[#6:9])=[#6:6]-[#6:10]=[#6:11]-[#6:12]=[#6:13]-[#6:14]=[#6:15](-[#6:20])-[#6:16]=[#6:17](-[#6](=[#8])-[#8]-[#6])-[#6:19])-[#6:2]-1=[#8:7])-[#8]",
            "reactions": [
                {
                    "substrate": "CC(=C\\C=C\\C=C\\C=C(/C)C(=O)C1C(=O)NC2(O)CCOC12)/C=C(\\C)C(=O)O",
                    "products": [
                        "COC(=O)C(C)=CC(C)=CC=CC=CC=C(C)C(=O)C1C(=O)NC2(O)CCOC12"
                    ],
                    "isIntermediate": true
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Heterologous expression"
                ],
                "references": [
                    "doi:10.1038/s41429-022-00529-3",
                    "doi:10.1016/j.chembiol.2013.07.004",
                    "doi:10.1080/09168451.2020.1725419"
                ]
            }
        }
    ]
}