{
    "accession": "MITE0000129",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "0000-0003-3002-6458",
                "0000-0001-7044-2419",
                "0000-0002-4187-2863",
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609",
                "0000-0003-0443-9902"
            ],
            "comment": "Initial entry. Reviewer partially fixed reactions:substrate, validation still not passing. Reviewer partially fixed reactions:products, validation still not passing. Reviewer 2 removed chirality information, reaction passes."
        },
        {
            "version": "2",
            "date": "2025-10-27",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609"
            ],
            "comment": "Replaced retired UniProtKB ID with UniParc ID"
        }
    ],
    "enzyme": {
        "name": "ThnJ",
        "description": "Aminotransferase",
        "references": [
            "doi:10.1002/cbic.201500670"
        ],
        "databaseIds": {
            "uniprot": "UPI00078CD00A",
            "genpept": "AMR44310.1"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Deamination"
            ],
            "reactionSMARTS": "[NH2:1][CH:2]([CH2:3][c:4]1[cH:5][nH:6][c:7]2[cH:8][c:9]([Cl:16])[cH:10][cH:11][c:12]12)[C:13]([OH:14])=[O:15]>>[O:1]=[C:2]([CH2:3][c:4]1[cH:5][nH:6][c:7]2[cH:8][c:9]([Cl:16])[cH:10][cH:11][c:12]12)[C:13]([OH:14])=[O:15]",
            "reactions": [
                {
                    "substrate": "NC(Cc1c[nH]c2cc(Cl)ccc12)C(=O)O",
                    "products": [
                        "O=C(O)C(=O)Cc1c[nH]c2cc(Cl)ccc12"
                    ],
                    "isIntermediate": false,
                    "description": "Should actually be L-chlorotryptophan."
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "In vitro assay",
                    "Heterologous expression",
                    "Knock-out studies"
                ],
                "references": [
                    "doi:10.1002/cbic.201500670"
                ]
            }
        }
    ]
}