{
    "accession": "MITE0000117",
    "status": "active",
    "comment": "Previously referenced retired MIBiG ID BGC0002069.",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "0000-0002-6077-7490",
                "0000-0002-4977-2541"
            ],
            "reviewers": [
                "0000-0003-0443-9902",
                "0000-0002-9747-3423"
            ],
            "comment": "Initial entry. Reviewer fixed reactionSMARTS:reactionSMARTS. Reviewer 2 changed enzyme and reaction description"
        },
        {
            "version": "2",
            "date": "2025-07-25",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609"
            ],
            "comment": "Added cofactor information"
        },
        {
            "version": "3",
            "date": "2025-08-26",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609"
            ],
            "comment": "Homogenized enzyme descriptions"
        },
        {
            "version": "4",
            "date": "2025-07-03",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609"
            ],
            "comment": "Removed retired MIBiG BGC ID."
        }
    ],
    "enzyme": {
        "name": "StoR",
        "description": "Oxidoreductase",
        "references": [
            "doi:10.1002/anie.201914154"
        ],
        "databaseIds": {
            "genpept": "TMU76675.1"
        },
        "cofactors": {
            "organic": [
                "NADP"
            ]
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Reduction"
            ],
            "description": "NADPH dependent reduction of exo-methylene in styrolide B to methyl group in styrolide A",
            "reactionSMARTS": "[#8:16]-[c:13]1[c:12][c:11][c:10](\\[#6:9]=[#6:8]\\[#6:4]-2=[#6:3]-[#6:2](=[#6:1])-[#8:6]-[#6:5]2=[O:7])[c:15][c:14]1>>[#6:1]-[#6@H:2]-1-[#8:6]-[#6:5](=[O:7])-[#6:4](\\[#6:8]=[#6:9]\\[c:10]2[c:11][c:12][c:13](-[#8:16])[c:14][c:15]2)=[#6:3]-1",
            "reactions": [
                {
                    "substrate": "C=C1C=C(/C=C/c2ccc(O)cc2)C(=O)O1",
                    "products": [
                        "C[C@@H]1C=C(/C=C/c2ccc(O)cc2)C(=O)O1"
                    ],
                    "isIntermediate": false
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Inference from genomic data and chemical structure"
                ],
                "references": [
                    "doi:10.1002/anie.201914154"
                ]
            }
        }
    ]
}