{
    "accession": "MITE0000107",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "0000-0003-3002-6458",
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0003-0443-9902"
            ],
            "comment": "Initial entry. Reviewer fixed reactionSMARTS:reactionSMARTS. Reviewer fixed reactions:products."
        },
        {
            "version": "2",
            "date": "2025-08-26",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609"
            ],
            "comment": "Homogenized enzyme descriptions"
        }
    ],
    "enzyme": {
        "name": "Mca",
        "description": "Amidase",
        "references": [
            "doi:10.1007/s10295-015-1694-6"
        ],
        "databaseIds": {
            "uniprot": "A0A0H5B8U5",
            "genpept": "BAR97454.1",
            "mibig": "BGC0001910"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Hydrolysis"
            ],
            "reactionSMARTS": "[#6:28]-[#6:27](=[O:29])-[#7:26]-[#6@@H:1](-[#6:2]-[#16:3]-[#6:4][C@:5]1([#8:6])[#6@@H:7](-[#8:8])-[#6:9]-[#6@H:10]2[C:11]([#6:12])([#6:13])[#6:14]-[#6:15]-[#6:16][C@:17]2([#6:18])[#6@H:19]1-[#6:20]\\[#6:21]=[#6:22](/[#6:23])-[#6:24]=[#6:25])-[#6:30](=[O:31])-[#7:32]-[#6:33]-1-[#6:34](-[#8:35])-[#6:36](-[#8:37])-[#6:38](-[#6:39]-[#8:40])-[#8:41]-[#6:42]-1-[#8:43]-[#6:44]-1-[#6:45](-[#8:46])-[#6:47](-[#8:48])-[#6:49](-[#8:50])-[#6:51](-[#8:52])-[#6:53]-1-[#8:54]>>[#6:28]-[#6:27](=[O:29])-[#7:26]-[#6@@H:1](-[#6:2]-[#16:3]-[#6:4][C@:5]1([#8:6])[#6@@H:7](-[#8:8])-[#6:9]-[#6@H:10]2[C:11]([#6:12])([#6:13])[#6:14]-[#6:15]-[#6:16][C@:17]2([#6:18])[#6@H:19]1-[#6:20]\\[#6:21]=[#6:22](/[#6:23])-[#6:24]=[#6:25])-[#6:30](-[#8:31])=[O:32].[#7:33]-[#6:34]-1-[#6:35](-[#8:36])-[#6:37](-[#8:38])-[#6:39](-[#6:40]-[#8:41])-[#8:42]-[#6:43]-1-[#8:44]-[#6:45]-1-[#6:46](-[#8:47])-[#6:48](-[#8:49])-[#6:50](-[#8:51])-[#6:52](-[#8:53])-[#6:54]-1-[#8]",
            "reactions": [
                {
                    "substrate": "C=C/C(C)=C/C[C@@H]1[C@@]2(C)CCCC(C)(C)[C@@H]2C[C@H](O)[C@@]1(O)CSC[C@H](NC(C)=O)C(=O)NC1C(OC2C(O)C(O)C(O)C(O)C2O)OC(CO)C(O)C1O",
                    "products": [
                        "C=C/C(C)=C/C[C@@H]1[C@@]2(C)CCCC(C)(C)[C@@H]2C[C@H](O)[C@@]1(O)CSC[C@H](NC(C)=O)C(=O)O",
                        "NC1C(OC2C(O)C(O)C(O)C(O)C2O)OC(CO)C(O)C1O"
                    ],
                    "isIntermediate": false
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Knock-out studies"
                ],
                "references": [
                    "doi:10.1007/s10295-015-1694-6"
                ]
            }
        }
    ]
}