{
    "accession": "MITE0000105",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "0000-0003-3002-6458",
                "0000-0001-6660-2715",
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0003-0443-9902"
            ],
            "comment": "Initial entry. Reviewer fixed reactionSMARTS:reactionSMARTS."
        },
        {
            "version": "2",
            "date": "2025-10-27",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0001-6534-6609"
            ],
            "comment": "Replaced retired UniProtKB ID with UniParc ID"
        }
    ],
    "enzyme": {
        "name": "GnmP",
        "description": "Persulfide methyltransferase",
        "references": [
            "doi:10.1038/s41467-021-25798-8"
        ],
        "databaseIds": {
            "uniprot": "UPI000938C7BA",
            "genpept": "ATY69565.1",
            "mibig": "BGC0001611"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Methylation"
            ],
            "reactionSMARTS": "[#6:1]\\[#6:2]-1=[#6:3]/[#6:4]-[#6:5](=[#6:6])\\[#6:7]=[#6:8]\\[#6:9](\\[#6:10])=[#6:11]/[c:12]2[c:13][s:14][c:15]([n:16]2)[C:17]2([#6:18]-[#6:19]2)[#7:20]-[#6:21](=[O:22])-[#6:23][C@:24]([#6:25]-[#6:26](-[#8:27])=[O:28])([#6:29]-[#6:30]1)[#16:31]-[#16:32]>>[#6:1]-[#16:2]-[#16:3][C@@:4]1([#6:5]-[#6:6](-[#8:7])=[O:8])[#6:9]-[#6:10]\\[#6:11](-[#6:12])=[#6:13]\\[#6:14]-[#6:15](=[#6:16])\\[#6:17]=[#6:18]\\[#6:19](\\[#6:20])=[#6:21]/[c:22]2[c:23][s:24][c:25]([n:26]2)[C:27]2([#6:28]-[#6:29]2)[#7:30]-[#6:31](=[O:32])-[#6]1",
            "reactions": [
                {
                    "substrate": "C=C1/C=C/C(C)=C\\c2csc(n2)C2(CC2)NC(=O)C[C@@](CC(=O)O)(SS)CC/C(C)=C/C1",
                    "products": [
                        "C=C1/C=C/C(C)=C\\c2csc(n2)C2(CC2)NC(=O)C[C@@](CC(=O)O)(SSC)CC/C(C)=C/C1"
                    ],
                    "isIntermediate": false
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "In vitro assay",
                    "Knock-out studies"
                ],
                "references": [
                    "doi:10.1038/s41467-021-25798-8"
                ]
            }
        }
    ]
}