{
    "accession": "MITE0000084",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "0000-0003-3002-6458"
            ],
            "reviewers": [
                "0000-0001-6406-4394"
            ],
            "comment": "Initial entry. Reviewer 1 added descriptions to reactions."
        }
    ],
    "enzyme": {
        "name": "NapB2",
        "description": "Monooxygenase",
        "references": [
            "doi:10.1074/jbc.M611046200"
        ],
        "databaseIds": {
            "uniprot": "A7KGZ3",
            "genpept": "ABS50452.1",
            "mibig": "BGC0001079"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Oxidation"
            ],
            "description": "Oxidation of 1,3,6,8-tetrahydroxynaphthalene (THN) to flaviolin.",
            "reactionSMARTS": "[#8:14]-[c:8]1[c:9][c:10](-[#8:12])[c:1]2[c:2](-[#8:11])[c:3][c:4](-[#8:13])[c:5][c:6]2[c:7]1>>[#8:13]-[c:4]1[c:3][c:2](-[#8:11])[c:1]2[c:6]([c:5]1)[c:7](=[O])[c:8](-[#8:14])[c:9][c:10]2=[O:12]",
            "reactions": [
                {
                    "substrate": "Oc1cc(O)c2c(O)cc(O)cc2c1",
                    "products": [
                        "O=C1C(O)=CC(=O)c2c(O)cc(O)cc21"
                    ],
                    "isIntermediate": true,
                    "description": "Oxidation of 1,3,6,8-tetrahydroxynaphthalene (THN) to flaviolin."
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Inference from genomic data and chemical structure"
                ],
                "references": [
                    "doi:10.1074/jbc.M611046200",
                    "doi:10.1021/ja201088k"
                ]
            }
        }
    ]
}